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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620515
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Olr1
Name: oxidized low density lipoprotein receptor 1
Acc ID: CHEBI:16243
Term: quercetin
Definition: A pentahydroxyflavone having the five hydroxy groups placed at the 3-, 3'-, 4'-, 5- and 7-positions. It is one of the most abundant flavonoids in edible vegetables, fruit and wine.
Chemical ID: MESH:D011794
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Olr1affects expressionEXP 6480464CTDQuercetin affects the expression of OLR1 mRNAPMID:18178720
Olr1multiple interactionsEXP 6480464CTDQuercetin affects the reaction [Dehydroepiandrosterone results in increased expression of OLR1 protein]; Quercetin inhibits the reaction [Dehydroepiandrosterone results in increased expression of OLR1 mRNA]PMID:27634381
Olr1multiple interactionsISOOLR1 (Homo sapiens)6480464CTD[Quercetin co-treated with Ascorbic Acid] results in increased expression of OLR1 mRNA; Quercetin inhibits the reaction [Lipids results in increased expression of OLR1]PMID:16891912 PMID:17639512
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