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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3770
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Star
Name: steroidogenic acute regulatory protein
Acc ID: CHEBI:16243
Term: quercetin
Definition: A pentahydroxyflavone having the five hydroxy groups placed at the 3-, 3'-, 4'-, 5- and 7-positions. It is one of the most abundant flavonoids in edible vegetables, fruit and wine.
Chemical ID: MESH:D011794
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Starmultiple interactionsEXP 6480464CTDQuercetin inhibits the reaction [[Atrazine co-treated with Bucladesine] results in increased expression of STAR mRNA]; Quercetin inhibits the reaction [Atrazine results in increased expression of STAR mRNA]; Quercetin inhibits the reaction [FSHB protein promotes the reaction [Atrazine results in increased expression of STAR mRNA]]PMID:22372587 PMID:23200735
Starincreases expressionISOStar (Mus musculus)6480464CTDQuercetin results in increased expression of STAR mRNAPMID:17332522
Starmultiple interactionsISOStar (Mus musculus)6480464CTDEgtazic Acid inhibits the reaction [Quercetin results in increased expression of STAR mRNA]; Quercetin promotes the reaction [Cyclic AMP results in increased expression of STAR mRNA]; Vanadates inhibits the reaction [Quercetin results in increased expression of STAR mRNA]PMID:17332522 PMID:28668616
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