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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3006
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Lhb
Name: luteinizing hormone subunit beta
Acc ID: CHEBI:16243
Term: quercetin
Definition: A pentahydroxyflavone having the five hydroxy groups placed at the 3-, 3'-, 4'-, 5- and 7-positions. It is one of the most abundant flavonoids in edible vegetables, fruit and wine.
Chemical ID: MESH:D011794
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lhbmultiple interactionsEXP 6480464CTDQuercetin inhibits the reaction [Cadmium Chloride results in decreased expression of LHB protein]; Quercetin inhibits the reaction [estradiol 3-benzoate results in decreased secretion of LHB protein]; Quercetin inhibits the reaction [Fenitrothion results in decreased secretion of LHB protein]; Quercetin inhibits the reaction [manganese chloride results in decreased expression of LHB protein]; Quercetin inhibits the reaction [Petroleum results in decreased expression of LHB protein]PMID:22356231 PMID:24316378 PMID:25046308 PMID:26264430 PMID:28040552
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