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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1563614
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tnfrsf11a
Name: TNF receptor superfamily member 11A
Acc ID: CHEBI:16243
Term: quercetin
Definition: A pentahydroxyflavone having the five hydroxy groups placed at the 3-, 3'-, 4'-, 5- and 7-positions. It is one of the most abundant flavonoids in edible vegetables, fruit and wine.
Chemical ID: MESH:D011794
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tnfrsf11aincreases expressionISOTNFRSF11A (Homo sapiens)6480464CTDQuercetin results in increased expression of TNFRSF11A mRNAPMID:21632981
Tnfrsf11amultiple interactionsISOTnfrsf11a (Mus musculus)6480464CTDQuercetin inhibits the reaction [TNFSF11 protein results in increased expression of TNFRSF11A mRNA]PMID:16434028
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