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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1553692
Species: Mus musculus
RGD Object: Gene
Symbol: Snai1
Name: snail family zinc finger 1
Acc ID: CHEBI:16243
Term: quercetin
Definition: A pentahydroxyflavone having the five hydroxy groups placed at the 3-, 3'-, 4'-, 5- and 7-positions. It is one of the most abundant flavonoids in edible vegetables, fruit and wine.
Chemical ID: MESH:D011794
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Snai1decreases expressionISOSNAI1 (Homo sapiens)6480464CTDQuercetin results in decreased expression of SNAI1 mRNA; Quercetin results in decreased expression of SNAI1 proteinPMID:33070227
Snai1increases expressionISOSNAI1 (Homo sapiens)6480464CTDQuercetin results in increased expression of SNAI1 mRNAPMID:21632981
Snai1multiple interactionsISOSNAI1 (Homo sapiens)6480464CTDSHH protein inhibits the reaction [Quercetin results in decreased expression of SNAI1 protein]PMID:33070227
Snai1multiple interactionsISOSnai1 (Rattus norvegicus)6480464CTDQuercetin inhibits the reaction [[Methylnitrosourea co-treated with Testosterone] results in increased expression of SNAI1 mRNA]PMID:25164625
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