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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 734175
Species: Mus musculus
RGD Object: Gene
Symbol: Cyba
Name: cytochrome b-245, alpha polypeptide
Acc ID: CHEBI:16240
Term: hydrogen peroxide
Definition: An inorganic peroxide consisting of two hydroxy groups joined by a covalent oxygen-oxygen single bond.
Chemical ID: MESH:D006861
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cybaincreases expressionISOCyba (Rattus norvegicus)6480464CTDHydrogen Peroxide results in increased expression of CYBA mRNA; Hydrogen Peroxide results in increased expression of CYBA proteinPMID:23270704
Cybaincreases expressionISOCYBA (Homo sapiens)6480464CTDHydrogen Peroxide results in increased expression of CYBA mRNA; Hydrogen Peroxide results in increased expression of CYBA proteinPMID:25305479 PMID:31586451
Cybamultiple interactionsISOCyba (Rattus norvegicus)6480464CTD4-chlorobenzyltetrahydroberberine inhibits the reaction [Hydrogen Peroxide results in increased expression of CYBA mRNA]; 4-chlorobenzyltetrahydroberberine inhibits the reaction [Hydrogen Peroxide results in increased expression of CYBA protein]; acetovanillone inhibits the reaction [Hydrogen Peroxide results in increased expression of CYBA mRNA]; acetovanillone inhibits the reaction [Hydrogen Peroxide results in increased expression of CYBA protein]PMID:23270704
Cybamultiple interactionsISOCYBA (Homo sapiens)6480464CTDanagliptin inhibits the reaction [Hydrogen Peroxide results in increased expression of CYBA mRNA]; Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of CYBA mRNA]; Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of CYBA protein]; Plant Extracts inhibits the reaction [Hydrogen Peroxide results in increased expression of CYBA mRNA]; Plant Extracts inhibits the reaction [Hydrogen Peroxide results in increased expression of CYBA protein]; Polysaccharides inhibits the reaction [Hydrogen Peroxide results in increased expression of CYBA mRNA]; Polysaccharides inhibits the reaction [Hydrogen Peroxide results in increased expression of CYBA protein]PMID:25305479 PMID:31586451
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