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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733969
Species: Mus musculus
RGD Object: Gene
Symbol: Ikbkb
Name: inhibitor of kappaB kinase beta
Acc ID: CHEBI:16240
Term: hydrogen peroxide
Definition: An inorganic peroxide consisting of two hydroxy groups joined by a covalent oxygen-oxygen single bond.
Chemical ID: MESH:D006861
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ikbkbaffects response to substanceEXP 6480464CTDIKBKB protein affects the susceptibility to Hydrogen PeroxidePMID:20159942
Ikbkbmultiple interactionsEXP 6480464CTDHydrogen Peroxide inhibits the reaction [Melitten inhibits the reaction [Nitroprusside results in increased activity of IKBKB protein]]PMID:17067557
Ikbkbmultiple interactionsISOIKBKB (Homo sapiens)6480464CTDIKBKB protein affects the reaction [Hydrogen Peroxide results in increased expression of MMP9 mRNA]PMID:26514923
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