Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732664
Species: Homo sapiens
RGD Object: Gene
Symbol: PDPK1
Name: 3-phosphoinositide dependent protein kinase 1
Acc ID: CHEBI:16240
Term: hydrogen peroxide
Definition: An inorganic peroxide consisting of two hydroxy groups joined by a covalent oxygen-oxygen single bond.
Chemical ID: MESH:D006861
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PDPK1increases phosphorylationISOPdpk1 (Mus musculus)6480464CTDHydrogen Peroxide results in increased phosphorylation of PDPK1 proteinPMID:27494022
PDPK1multiple interactionsISOPdpk1 (Mus musculus)6480464CTDPI103 inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of PDPK1 protein]; Quercetin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of PDPK1 protein]PMID:27494022
Go Back to source page   Continue to Ontology report