GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Hsf1 | increases activity | ISO | HSF1 (Homo sapiens) | 6480464 | CTD | Hydrogen Peroxide results in increased activity of HSF1 protein | PMID:34170685 | Hsf1 | increases expression | ISO | HSF1 (Homo sapiens) | 6480464 | CTD | Hydrogen Peroxide results in increased expression of HSF1 mRNA; Hydrogen Peroxide results in increased expression of HSF1 protein | PMID:19401454 PMID:30309986 | Hsf1 | multiple interactions | ISO | Hsf1 (Rattus norvegicus) | 6480464 | CTD | HSF1 protein inhibits the reaction [Hydrogen Peroxide affects the localization of HMGB1 protein]; HSF1 protein inhibits the reaction [Hydrogen Peroxide results in increased expression of and results in increased secretion of HMGB1 protein] | PMID:22246807 | | ||||||||||||||||||||||
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