GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mtor | multiple interactions | EXP | | 6480464 | CTD | [Rotenone results in increased abundance of Hydrogen Peroxide] inhibits the reaction [MTOR protein results in increased phosphorylation of EIF4EBP1 protein]; [Rotenone results in increased abundance of Hydrogen Peroxide] inhibits the reaction [MTOR protein results in increased phosphorylation of RPS6KB1 protein]; CAT protein inhibits the reaction [[Rotenone results in increased abundance of Hydrogen Peroxide] inhibits the reaction [MTOR protein results in increased phosphorylation of EIF4EBP1 protein]]; CAT protein inhibits the reaction [[Rotenone results in increased abundance of Hydrogen Peroxide] inhibits the reaction [MTOR protein results in increased phosphorylation of RPS6KB1 protein]]; MTOR protein inhibits the reaction [Rotenone results in increased abundance of Hydrogen Peroxide] | PMID:25304210 | Mtor | decreases phosphorylation | ISO | MTOR (Homo sapiens) | 6480464 | CTD | Hydrogen Peroxide results in decreased phosphorylation of MTOR protein | PMID:32043704 | Mtor | increases phosphorylation | ISO | MTOR (Homo sapiens) | 6480464 | CTD | Hydrogen Peroxide results in increased phosphorylation of MTOR protein | PMID:27451028 | Mtor | multiple interactions | ISO | MTOR (Homo sapiens) | 6480464 | CTD | 3-methyladenine inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of MTOR protein]; [Hydrogen Peroxide co-treated with N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride] promotes the reaction [ATM protein modified form binds to AKT1 protein binds to MTOR protein binds to IKBKG protein]; gingerol inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MTOR protein]; KISS1 protein affects the reaction [Hydrogen Peroxide results in decreased phosphorylation of MTOR protein]; MTOR protein affects the reaction [N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride promotes the reaction [Hydrogen Peroxide results in increased phosphorylation of AKT1 protein]] | PMID:27451028 PMID:30296409 PMID:32043704 | | ||||||||||||||||||||||
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