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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 67366
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pla2g4a
Name: phospholipase A2 group IVA
Acc ID: CHEBI:16240
Term: hydrogen peroxide
Definition: An inorganic peroxide consisting of two hydroxy groups joined by a covalent oxygen-oxygen single bond.
Chemical ID: MESH:D006861
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionEXP 6480464CTDHydrogen Peroxide results in decreased expression of PLA2G4A mRNA

PMID:15683734
multiple interactionsEXP 6480464CTDAcetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of PLA2G4A mRNA], SB 203580 inhibits the reaction [Hydrogen Peroxide results in decreased expression of PLA2G4A mRNA], U 0126 inhibits the reaction [Hydrogen Peroxide results in decreased expression of PLA2G4A mRNA]

PMID:15683734
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.