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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62283
Species: Mus musculus
RGD Object: Gene
Symbol: Smc1a
Name: structural maintenance of chromosomes 1A
Acc ID: CHEBI:16240
Term: hydrogen peroxide
Definition: An inorganic peroxide consisting of two hydroxy groups joined by a covalent oxygen-oxygen single bond.
Chemical ID: MESH:D006861
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Smc1aincreases phosphorylationISOSMC1A (Homo sapiens)6480464CTDHydrogen Peroxide results in increased phosphorylation of SMC1A proteinPMID:24933654
Smc1amultiple interactionsISOSMC1A (Homo sapiens)6480464CTD2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of SMC1A protein]; 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [resveratrol promotes the reaction [Hydrogen Peroxide results in increased phosphorylation of SMC1A protein]]; resveratrol promotes the reaction [Hydrogen Peroxide results in increased phosphorylation of SMC1A protein]PMID:24933654
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