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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3960
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Vhl
Name: von Hippel-Lindau tumor suppressor
Acc ID: CHEBI:16240
Term: hydrogen peroxide
Definition: An inorganic peroxide consisting of two hydroxy groups joined by a covalent oxygen-oxygen single bond.
Chemical ID: MESH:D006861
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Vhlaffects expressionISOVHL (Homo sapiens)6480464CTDHydrogen Peroxide affects the expression of VHL mRNAPMID:21179406
Vhlaffects response to substanceISOVHL (Homo sapiens)6480464CTDVHL protein mutant form affects the susceptibility to Hydrogen PeroxidePMID:18515279
Vhlmultiple interactionsISOVHL (Homo sapiens)6480464CTDVHL protein mutant form affects the reaction [Deferoxamine results in decreased susceptibility to Hydrogen Peroxide]PMID:18515279
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