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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3227
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Odc1
Name: ornithine decarboxylase 1
Acc ID: CHEBI:16240
Term: hydrogen peroxide
Definition: An inorganic peroxide consisting of two hydroxy groups joined by a covalent oxygen-oxygen single bond.
Chemical ID: MESH:D006861
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Odc1affects expressionISOODC1 (Homo sapiens)6480464CTDHydrogen Peroxide affects the expression of ODC1 mRNAPMID:20044591
Odc1decreases activityISOODC1 (Homo sapiens)6480464CTDHydrogen Peroxide results in decreased activity of ODC1 proteinPMID:3986791
Odc1multiple interactionsISOOdc1 (Mus musculus)6480464CTDIron promotes the reaction [Hydrogen Peroxide results in increased activity of ODC1 protein]; Iron-Dextran Complex promotes the reaction [Hydrogen Peroxide results in increased activity of ODC1 protein]PMID:12065085
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