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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1319531
Species: Homo sapiens
RGD Object: Gene
Symbol: SLC7A11
Name: solute carrier family 7 member 11
Acc ID: CHEBI:16240
Term: hydrogen peroxide
Definition: An inorganic peroxide consisting of two hydroxy groups joined by a covalent oxygen-oxygen single bond.
Chemical ID: MESH:D006861
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SLC7A11affects expressionEXP 6480464CTDHydrogen Peroxide affects the expression of SLC7A11 mRNAPMID:23410634
SLC7A11decreases expressionEXP 6480464CTDHydrogen Peroxide results in decreased expression of SLC7A11 mRNAPMID:18951874
SLC7A11increases expressionEXP 6480464CTDHydrogen Peroxide results in increased expression of SLC7A11 mRNAPMID:12414654
SLC7A11multiple interactionsEXP 6480464CTD[[[Bilirubin results in increased activity of [SLC7A11 protein co-treated with SLC3A2 protein]] which results in increased uptake of Cystine] which results in increased abundance of Glutathione] which results in decreased susceptibility to Hydrogen PeroxidePMID:22216172
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