GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Bach1 | increases expression | EXP | | 6480464 | CTD | Hydrogen Peroxide results in increased expression of BACH1 protein | PMID:30660577 | Bach1 | multiple interactions | EXP | | 6480464 | CTD | BACH1 protein inhibits the reaction [SIRT6 protein inhibits the reaction [Hydrogen Peroxide results in increased activity of CASP3 protein]]; SIRT6 protein inhibits the reaction [Hydrogen Peroxide results in increased expression of BACH1 protein] | PMID:30660577 | Bach1 | decreases expression | ISO | BACH1 (Homo sapiens) | 6480464 | CTD | Hydrogen Peroxide results in decreased expression of BACH1 protein | PMID:28285367 | Bach1 | increases expression | ISO | Bach1 (Mus musculus) | 6480464 | CTD | Hydrogen Peroxide results in increased expression of BACH1 mRNA; Hydrogen Peroxide results in increased expression of BACH1 protein | PMID:31194955 | Bach1 | multiple interactions | ISO | BACH1 (Homo sapiens) | 6480464 | CTD | Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in decreased expression of BACH1 protein] | PMID:28285367 | Bach1 | multiple interactions | ISO | Bach1 (Mus musculus) | 6480464 | CTD | BACH1 protein affects the reaction [Hydrogen Peroxide results in increased expression of NFE2L2 protein]; BACH1 protein inhibits the reaction [Hydrogen Peroxide results in increased expression of HMOX mRNA]; BACH1 protein inhibits the reaction [Hydrogen Peroxide results in increased expression of NQO1 mRNA] | PMID:31194955 | | ||||||||||||||||||||||
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