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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10118
Species: Mus musculus
RGD Object: Gene
Symbol: Agt
Name: angiotensinogen
Acc ID: CHEBI:16240
Term: hydrogen peroxide
Definition: An inorganic peroxide consisting of two hydroxy groups joined by a covalent oxygen-oxygen single bond.
Chemical ID: MESH:D006861
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Agtincreases abundanceEXP 6480464CTDAGT protein modified form results in increased abundance of Hydrogen PeroxidePMID:12606818
Agtincreases expressionEXP 6480464CTDHydrogen Peroxide results in increased expression of AGT mRNA; Hydrogen Peroxide results in increased expression of AGT protein modified formPMID:30710622
Agtmultiple interactionsEXP 6480464CTD[GMFB protein co-treated with AGT protein] results in increased abundance of Hydrogen PeroxidePMID:12791701
Agtaffects expressionISOAGT (Homo sapiens)6480464CTDHydrogen Peroxide affects the expression of AGT mRNAPMID:20044591
Agtincreases abundanceISOAgt (Rattus norvegicus)6480464CTDAGT protein modified form results in increased abundance of Hydrogen Peroxide; AGT protein results in increased abundance of Hydrogen PeroxidePMID:10712386 PMID:20881940
Agtincreases chemical synthesisISOAgt (Rattus norvegicus)6480464CTDAGT protein modified form results in increased chemical synthesis of Hydrogen PeroxidePMID:29609002
Agtincreases expressionISOAgt (Rattus norvegicus)6480464CTDHydrogen Peroxide results in increased expression of AGT protein modified formPMID:15867141
Agtmultiple interactionsISOAgt (Rattus norvegicus)6480464CTDHydrogen Peroxide promotes the reaction [Glucose results in increased expression of AGT mRNA]; Hydrogen Peroxide promotes the reaction [Glucose results in increased expression of AGT protein]; isorhapontigenin inhibits the reaction [AGT protein results in increased abundance of Hydrogen Peroxide]PMID:12130563 PMID:15607907
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