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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68631
Species: Mus musculus
RGD Object: Gene
Symbol: Dlg4
Name: discs large MAGUK scaffold protein 4
Acc ID: CHEBI:16236
Term: ethanol
Definition: A primary alcohol that is ethane in which one of the hydrogens is substituted by a hydroxy group.
Chemical ID: MESH:D000431
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Dlg4affects splicingEXP 6480464CTDEthanol affects the splicing of DLG4 mRNAPMID:30319688
Dlg4decreases expressionEXP 6480464CTDEthanol results in decreased expression of DLG4 proteinPMID:35181401
Dlg4increases expressionEXP 6480464CTDEthanol results in increased expression of DLG4 mRNAPMID:21955143
Dlg4multiple interactionsEXP 6480464CTD[Ethanol co-treated with High Fructose Corn Syrup co-treated with lard] results in decreased expression of DLG4 protein; m-trifluoromethyl-diphenyl diselenide inhibits the reaction [[Ethanol co-treated with High Fructose Corn Syrup co-treated with lard] results in decreased expression of DLG4 protein]PMID:37054933
Dlg4increases expressionISODlg4 (Rattus norvegicus)6480464CTDEthanol results in increased expression of DLG4 mRNAPMID:20655511
Dlg4multiple interactionsISODlg4 (Rattus norvegicus)6480464CTDN-methyl-N-(6-methoxy-1-phenyl-1,2,3,4-tetrahydronaphthalen-2-ylmethyl)aminomethylcarboxylic acid inhibits the reaction [Ethanol results in increased expression of DLG4 mRNA]PMID:20655511
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