Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 631344
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abca1
Name: ATP binding cassette subfamily A member 1
Acc ID: CHEBI:16236
Term: ethanol
Definition: A primary alcohol that is ethane in which one of the hydrogens is substituted by a hydroxy group.
Chemical ID: MESH:D000431
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionEXP 6480464CTDEthanol results in decreased expression of ABCA1 mRNA, Ethanol results in decreased expression of ABCA1 protein

PMID:26220516
increases expressionEXP 6480464CTDEthanol results in increased expression of ABCA1 mRNA, Ethanol results in increased expression of ABCA1 protein

PMID:17478430
multiple interactionsEXP 6480464CTDEthanol results in increased expression of and affects the localization of ABCA1 protein

PMID:17478430
affects splicingISORGD:13323546480464CTDEthanol affects the splicing of ABCA1 mRNA

PMID:30319688
increases expressionISORGD:13323546480464CTDEthanol results in increased expression of ABCA1 mRNA

PMID:30319688
increases expressionISORGD:7361576480464CTDEthanol results in increased expression of ABCA1 protein

PMID:17478430
Go Back to source page   Continue to Ontology report

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.