GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ddit3 | increases expression | EXP | | 6480464 | CTD | Ethanol results in increased expression of DDIT3 mRNA; Ethanol results in increased expression of DDIT3 protein | PMID:23544086 PMID:28119953 | Ddit3 | multiple interactions | EXP | | 6480464 | CTD | [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] results in increased expression of DDIT3 protein; Ethanol promotes the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased expression of DDIT3 protein]; Hemin inhibits the reaction [[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] results in increased expression of DDIT3 protein]; ursodoxicoltaurine inhibits the reaction [Ethanol results in increased expression of DDIT3 protein]; zinc protoporphyrin promotes the reaction [[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] results in increased expression of DDIT3 protein] | PMID:23544086 PMID:26747958 | Ddit3 | increases expression | ISO | Ddit3 (Mus musculus) | 6480464 | CTD | Ethanol results in increased expression of DDIT3 mRNA; Ethanol results in increased expression of DDIT3 protein | PMID:27983966 PMID:28119953 | Ddit3 | increases expression | ISO | DDIT3 (Homo sapiens) | 6480464 | CTD | Ethanol results in increased expression of DDIT3 protein | PMID:24224909 | Ddit3 | multiple interactions | ISO | Ddit3 (Mus musculus) | 6480464 | CTD | Cimetidine inhibits the reaction [Ethanol results in increased expression of DDIT3 protein]; Drugs, Chinese Herbal inhibits the reaction [Ethanol results in increased expression of DDIT3 protein]; Hydralazine inhibits the reaction [Ethanol results in increased expression of DDIT3 mRNA]; Hydralazine inhibits the reaction [Ethanol results in increased expression of DDIT3 protein] | PMID:27983966 PMID:28119953 | Ddit3 | multiple interactions | ISO | DDIT3 (Homo sapiens) | 6480464 | CTD | [[Gasoline co-treated with Ethanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of DDIT3 mRNA; Resveratrol inhibits the reaction [Ethanol results in increased expression of DDIT3 protein] | PMID:24224909 PMID:29432896 | | ||||||||||||||||||||||
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