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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620886
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Txnip
Name: thioredoxin interacting protein
Acc ID: CHEBI:16236
Term: ethanol
Definition: A primary alcohol that is ethane in which one of the hydrogens is substituted by a hydroxy group.
Chemical ID: MESH:D000431
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Txnipincreases expressionISOTxnip (Mus musculus)6480464CTDEthanol results in increased expression of TXNIP proteinPMID:32492475
Txnipmultiple interactionsISOTXNIP (Homo sapiens)6480464CTD[[Gasoline co-treated with Ethanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of TXNIP mRNAPMID:29432896
Txnipmultiple interactionsISOTxnip (Mus musculus)6480464CTD[ethylene dichloride co-treated with Ethanol] results in increased expression of TXNIP protein; allyl sulfide inhibits the reaction [[ethylene dichloride co-treated with Ethanol] results in increased expression of TXNIP protein]; FOXO1 protein inhibits the reaction [Ethanol results in increased expression of TXNIP protein]PMID:32492475 PMID:37150348
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