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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61847
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gpam
Name: glycerol-3-phosphate acyltransferase, mitochondrial
Acc ID: CHEBI:16236
Term: ethanol
Definition: A primary alcohol that is ethane in which one of the hydrogens is substituted by a hydroxy group.
Chemical ID: MESH:D000431
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gpamdecreases expressionISOGPAM (Homo sapiens)6480464CTDEthanol results in decreased expression of GPAM mRNAPMID:23378141
Gpamincreases expressionISOGpam (Mus musculus)6480464CTDEthanol results in increased expression of GPAM mRNAPMID:18755807 PMID:20637825 PMID:30319688
Gpammultiple interactionsISOGpam (Mus musculus)6480464CTD[Zinc deficiency co-treated with Ethanol] results in decreased expression of GPAM mRNA; resveratrol inhibits the reaction [Ethanol results in increased expression of GPAM mRNA]; tectoridin inhibits the reaction [Ethanol results in increased expression of GPAM mRNA]PMID:18755807 PMID:20637825 PMID:24155903
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