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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2225
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Btg2
Name: BTG anti-proliferation factor 2
Acc ID: CHEBI:16236
Term: ethanol
Definition: A primary alcohol that is ethane in which one of the hydrogens is substituted by a hydroxy group.
Chemical ID: MESH:D000431
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Btg2decreases expressionEXP 6480464CTDEthanol results in decreased expression of BTG2 mRNAPMID:15353170
Btg2increases expressionISOBtg2 (Mus musculus)6480464CTDEthanol results in increased expression of BTG2 mRNA; Ethanol results in increased expression of BTG2 proteinPMID:28095641
Btg2multiple interactionsISOBtg2 (Mus musculus)6480464CTDAM 251 inhibits the reaction [Ethanol results in increased expression of BTG2 mRNA]; BTG2 protein affects the reaction [Ethanol results in increased expression of BTG2 mRNA]; BTG2 protein affects the reaction [Ethanol results in increased expression of CYP27A1 mRNA]; BTG2 protein affects the reaction [Ethanol results in increased expression of CYP7A1 mRNA]; BTG2 protein affects the reaction [Ethanol results in increased expression of CYP8B1 mRNA]; BTG2 protein affects the reaction [Ethanol results in increased expression of YY1 mRNA]; Melatonin inhibits the reaction [Ethanol results in increased expression of BTG2 protein]; MIR497 mRNA inhibits the reaction [Ethanol results in increased expression of BTG2 protein]PMID:28095641
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