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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2206
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bglap
Name: bone gamma-carboxyglutamate protein
Acc ID: CHEBI:16236
Term: ethanol
Definition: A primary alcohol that is ethane in which one of the hydrogens is substituted by a hydroxy group.
Chemical ID: MESH:D000431
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bglapdecreases expressionEXP 6480464CTDEthanol results in decreased expression of BGLAP mRNA; Ethanol results in decreased expression of BGLAP proteinPMID:23376407 PMID:31887396
Bglapmultiple interactionsEXP 6480464CTDEnalapril inhibits the reaction [Ethanol results in decreased expression of BGLAP mRNA]; Ethanol promotes the reaction [lead acetate results in decreased expression of BGLAP protein]PMID:23376407 PMID:31887396
Bglapdecreases expressionISOBglap (Mus musculus)6480464CTDEthanol results in decreased expression of BGLAP mRNA; Ethanol results in decreased expression of BGLAP proteinPMID:22892342 PMID:34755883
Bglapmultiple interactionsISOBglap (Mus musculus)6480464CTD[Genistein co-treated with Ethanol] results in increased expression of BGLAP mRNA; Vitamin D affects the reaction [Ethanol results in decreased expression of BGLAP mRNA]PMID:22892342 PMID:24872432
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