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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2070
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Agtr1a
Name: angiotensin II receptor, type 1a
Acc ID: CHEBI:16236
Term: ethanol
Definition: A primary alcohol that is ethane in which one of the hydrogens is substituted by a hydroxy group.
Chemical ID: MESH:D000431
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Agtr1adecreases expressionEXP 6480464CTDEthanol results in decreased expression of AGTR1A mRNA; Ethanol results in decreased expression of AGTR1A proteinPMID:31887396
Agtr1aincreases expressionEXP 6480464CTDEthanol results in increased expression of AGTR1A mRNAPMID:25151222 PMID:29548890
Agtr1amultiple interactionsEXP 6480464CTDEthanol affects the reaction [Dietary Fats affects the expression of AGTR1 mRNA]; Ethanol affects the reaction [Dietary Fats affects the expression of AGTR1 protein]PMID:31811911
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