GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Adora1 | affects splicing | ISO | Adora1 (Mus musculus) | 6480464 | CTD | Ethanol affects the splicing of ADORA1 mRNA | PMID:30319688 | Adora1 | increases expression | ISO | Adora1 (Mus musculus) | 6480464 | CTD | Ethanol results in increased expression of ADORA1 mRNA | PMID:35143882 | Adora1 | increases response to substance | ISO | Adora1 (Mus musculus) | 6480464 | CTD | ADORA1 gene mutant form results in increased susceptibility to Ethanol | PMID:23692951 | Adora1 | multiple interactions | ISO | Adora1 (Mus musculus) | 6480464 | CTD | [ADORA1 gene mutant form results in increased susceptibility to Ethanol] which results in increased expression of ACACA mRNA; [ADORA1 gene mutant form results in increased susceptibility to Ethanol] which results in increased expression of DGAT2 mRNA; [ADORA1 gene mutant form results in increased susceptibility to Ethanol] which results in increased expression of FASN mRNA; [ADORA1 gene mutant form results in increased susceptibility to Ethanol] which results in increased expression of PPARG mRNA; [ADORA1 gene mutant form results in increased susceptibility to Ethanol] which results in increased expression of SCD1 mRNA; ADORA1 gene mutant form promotes the reaction [Ethanol results in increased abundance of Triglycerides] | PMID:23692951 | | ||||||||||||||||||||||
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