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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1620920
Species: Mus musculus
RGD Object: Gene
Symbol: Dnmt3a
Name: DNA methyltransferase 3A
Acc ID: CHEBI:16236
Term: ethanol
Definition: A primary alcohol that is ethane in which one of the hydrogens is substituted by a hydroxy group.
Chemical ID: MESH:D000431
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Dnmt3aaffects expressionEXP 6480464CTDEthanol affects the expression of DNMT3A mRNAPMID:26730594
Dnmt3aaffects splicingEXP 6480464CTDEthanol affects the splicing of DNMT3A mRNAPMID:30319688
Dnmt3adecreases expressionEXP 6480464CTDEthanol results in decreased expression of DNMT3A proteinPMID:23395981
Dnmt3aincreases degradationEXP 6480464CTDEthanol results in increased degradation of DNMT3A proteinPMID:23395981
Dnmt3aincreases expressionEXP 6480464CTDEthanol results in increased expression of DNMT3A mRNAPMID:23395981
Dnmt3amultiple interactionsEXP 6480464CTDbenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Ethanol results in increased degradation of DNMT3A protein]PMID:23395981
Dnmt3aaffects expressionISODNMT3A (Homo sapiens)6480464CTDEthanol affects the expression of DNMT3A proteinPMID:35149083
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