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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1606836
Species: Homo sapiens
RGD Object: Gene
Symbol: PLOD2
Name: procollagen-lysine,2-oxoglutarate 5-dioxygenase 2
Acc ID: CHEBI:16236
Term: ethanol
Definition: A primary alcohol that is ethane in which one of the hydrogens is substituted by a hydroxy group.
Chemical ID: MESH:D000431
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PLOD2increases expressionEXP 6480464CTDEthanol results in increased expression of PLOD2 mRNAPMID:15997088 PMID:23378141
PLOD2multiple interactionsEXP 6480464CTD[[Gasoline co-treated with Ethanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of PLOD2 mRNA; [Ethanol co-treated with Folic Acid] results in increased expression of PLOD2 mRNAPMID:23378141 PMID:29432896
PLOD2multiple interactionsISOPlod2 (Mus musculus)6480464CTD[Carbon Tetrachloride co-treated with Ethanol] results in increased expression of PLOD2 mRNAPMID:30517762
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