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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1352787
Species: Homo sapiens
RGD Object: Gene
Symbol: XBP1
Name: X-box binding protein 1
Acc ID: CHEBI:16236
Term: ethanol
Definition: A primary alcohol that is ethane in which one of the hydrogens is substituted by a hydroxy group.
Chemical ID: MESH:D000431
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
XBP1decreases splicingISOXbp1 (Mus musculus)6480464CTDEthanol results in decreased splicing of XBP1 mRNAPMID:28119953
XBP1increases expressionISOXbp1 (Mus musculus)6480464CTDEthanol results in increased expression of XBP1 proteinPMID:29044621
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