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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1309275
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc7a11
Name: solute carrier family 7 member 11
Acc ID: CHEBI:16236
Term: ethanol
Definition: A primary alcohol that is ethane in which one of the hydrogens is substituted by a hydroxy group.
Chemical ID: MESH:D000431
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc7a11decreases expressionISOSlc7a11 (Mus musculus)6480464CTDEthanol results in decreased expression of SLC7A11 proteinPMID:33017621
Slc7a11increases expressionISOSlc7a11 (Mus musculus)6480464CTDEthanol results in increased expression of SLC7A11 mRNAPMID:30319688
Slc7a11multiple interactionsISOSLC7A11 (Homo sapiens)6480464CTD[CYP2E1 protein affects the susceptibility to Ethanol] which affects the expression of SLC7A11 protein; FXN protein affects the reaction [[CYP2E1 protein affects the susceptibility to Ethanol] which affects the expression of SLC7A11 protein]PMID:33017621
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