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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1304817
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Atg7
Name: autophagy related 7
Acc ID: CHEBI:16236
Term: ethanol
Definition: A primary alcohol that is ethane in which one of the hydrogens is substituted by a hydroxy group.
Chemical ID: MESH:D000431
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Atg7multiple interactionsEXP 6480464CTDEthanol promotes the reaction [Mirtazapine results in increased expression of ATG7 mRNA]; HMGB1 protein affects the reaction [Ethanol promotes the reaction [Mirtazapine results in increased expression of ATG7 mRNA]]PMID:35066094
Atg7increases expressionISOATG7 (Homo sapiens)6480464CTDEthanol results in increased expression of ATG7 mRNAPMID:24095927
Atg7increases expressionISOAtg7 (Mus musculus)6480464CTDEthanol results in increased expression of ATG7 mRNA; Ethanol results in increased expression of ATG7 proteinPMID:24095927 PMID:24492484
Atg7multiple interactionsISOATG7 (Homo sapiens)6480464CTDATG7 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of CCN1 protein]]PMID:34405320
Atg7multiple interactionsISOAtg7 (Mus musculus)6480464CTDATG7 mutant form inhibits the reaction [Ethanol results in increased lipidation of MAP1LC3B protein]; Dactinomycin inhibits the reaction [Ethanol results in increased expression of ATG7 protein]; Ethanol promotes the reaction [Mirtazapine results in increased expression of ATG7 mRNA]; FOXO3 protein affects the reaction [Ethanol results in increased expression of ATG7 mRNA]PMID:24095927 PMID:24492484 PMID:35066094
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