Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10828
Species: Mus musculus
RGD Object: Gene
Symbol: Jun
Name: jun proto-oncogene
Acc ID: CHEBI:16236
Term: ethanol
Definition: A primary alcohol that is ethane in which one of the hydrogens is substituted by a hydroxy group.
Chemical ID: MESH:D000431
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Junaffects expressionEXP 6480464CTDEthanol affects the expression of JUN mRNAPMID:30319688
Jundecreases expressionEXP 6480464CTDEthanol results in decreased expression of JUN mRNAPMID:19167417
Junincreases expressionEXP 6480464CTDEthanol results in increased expression of JUN mRNAPMID:20067348
Junmultiple interactionsEXP 6480464CTD[Ethanol co-treated with 4-Nitroquinoline-1-oxide] results in increased expression of JUN mRNAPMID:37406968
Jundecreases expressionISOJun (Rattus norvegicus)6480464CTDEthanol results in decreased expression of JUN mRNAPMID:20655511
Junincreases expressionISOJun (Rattus norvegicus)6480464CTDEthanol results in increased expression of JUN mRNAPMID:12065697 PMID:21999510
Junmultiple interactionsISOJun (Rattus norvegicus)6480464CTDEthanol results in increased expression of and results in increased activity of JUN protein; N-methyl-N-(6-methoxy-1-phenyl-1,2,3,4-tetrahydronaphthalen-2-ylmethyl)aminomethylcarboxylic acid inhibits the reaction [Ethanol results in decreased expression of JUN mRNA]PMID:20655511 PMID:21999510
Junmultiple interactionsISOJUN (Homo sapiens)6480464CTD[Ethanol co-treated with Folic Acid] results in increased expression of JUN mRNA; JUN promotes the reaction [Ethanol results in increased expression of and results in increased activity of RUNX2 protein]PMID:23378141 PMID:32198086
Go Back to source page   Continue to Ontology report