GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Igf1r | affects expression | EXP | | 6480464 | CTD | Ethanol affects the expression of IGF1R mRNA | PMID:30319688 | Igf1r | decreases expression | EXP | | 6480464 | CTD | Ethanol results in decreased expression of IGF1R mRNA | PMID:29524503 | Igf1r | increases expression | EXP | | 6480464 | CTD | Ethanol results in increased expression of IGF1R mRNA | PMID:30319688 | Igf1r | affects expression | ISO | Igf1r (Rattus norvegicus) | 6480464 | CTD | Ethanol affects the expression of IGF1R mRNA; Ethanol affects the expression of IGF1R protein | PMID:31039417 PMID:32535229 | Igf1r | decreases expression | ISO | Igf1r (Rattus norvegicus) | 6480464 | CTD | Ethanol results in decreased expression of IGF1R mRNA; Ethanol results in decreased expression of IGF1R protein modified form | PMID:31226463 | Igf1r | decreases expression | ISO | IGF1R (Homo sapiens) | 6480464 | CTD | Ethanol results in decreased expression of IGF1R mRNA; Ethanol results in decreased expression of IGF1R protein modified form | PMID:29524503 PMID:31226463 | Igf1r | increases activity | ISO | Igf1r (Rattus norvegicus) | 6480464 | CTD | Ethanol results in increased activity of IGF1R protein | PMID:19735724 | Igf1r | multiple interactions | ISO | Igf1r (Rattus norvegicus) | 6480464 | CTD | [Dietary Fats co-treated with Ethanol] results in increased expression of IGF1R mRNA; Ethanol affects the reaction [Dietary Fats affects the expression of IGF1R mRNA]; Ethanol affects the reaction [Dietary Fats affects the expression of IGF1R protein]; Polysaccharides promotes the reaction [Ethanol results in increased activity of IGF1R protein] | PMID:19735724 PMID:24275070 PMID:31811911 | |
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