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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1551988
Species: Mus musculus
RGD Object: Gene
Symbol: Parp1
Name: poly (ADP-ribose) polymerase family, member 1
Acc ID: CHEBI:16204
Term: phloroglucinol
Definition: A benzenetriol with hydroxy groups at position 1, 3 and 5.
Chemical ID: MESH:D010696
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Parp1increases cleavageISOPARP1 (Homo sapiens)6480464CTDPhloroglucinol analog results in increased cleavage of PARP1 protein; Phloroglucinol metabolite results in increased cleavage of PARP1 proteinPMID:22796323 PMID:23178381
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