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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737005
Species: Homo sapiens
RGD Object: Gene
Symbol: GPX1
Name: glutathione peroxidase 1
Acc ID: CHEBI:16170
Term: mercury(0)
Definition: Elemental mercury of oxidation state zero.
Chemical ID: MESH:D008628
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
GPX1affects response to substanceEXP 6480464CTDGPX1 gene SNP affects the susceptibility to MercuryPMID:22236634
GPX1increases expressionEXP 6480464CTDMercury results in increased expression of GPX1 proteinPMID:16451871
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