GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cyp1b1 | increases expression | ISO | Cyp1b1 (Mus musculus) | 6480464 | CTD | Mercury results in increased expression of CYP1B1 protein | PMID:22579925 PMID:23231920 | Cyp1b1 | multiple interactions | ISO | Cyp1b1 (Mus musculus) | 6480464 | CTD | Mercury affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]; Mercury inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein]; Mercury promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1B1 protein]; Mercury promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]; Mercury promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein] | PMID:22579925 PMID:23231920 | | ||||||||||||||||||||||
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