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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1551496
Species: Mus musculus
RGD Object: Gene
Symbol: Abcg2
Name: ATP binding cassette subfamily G member 2 (Junior blood group)
Acc ID: CHEBI:16130
Term: DDT
Definition: A chlorophenylethane that is 1,1,1-trichloro-2,2-diphenylethane substituted by additional chloro substituents at positions 4 of the phenyl substituents. It is a commonly used organochlorine insecticide.
Chemical ID: MESH:D003634
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcg2decreases activityISOABCG2 (Homo sapiens)6480464CTDDDT metabolite results in decreased activity of ABCG2 proteinPMID:23169446
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