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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730951
Species: Homo sapiens
RGD Object: Gene
Symbol: NOS2
Name: nitric oxide synthase 2
Acc ID: CHEBI:16118
Term: berberine
Definition: A botanical anti-fungal agent that has formula C20H18NO4.
Chemical ID: MESH:D001599
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NOS2multiple interactionsISONos2 (Mus musculus)6480464CTDBerberine inhibits the reaction [Carbon Tetrachloride results in increased expression of NOS2 protein]PMID:21095217
NOS2multiple interactionsISONos2 (Rattus norvegicus)6480464CTDBerberine inhibits the reaction [Bleomycin results in increased expression of NOS2 protein]PMID:23523906
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