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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735634
Species: Mus musculus
RGD Object: Gene
Symbol: Scarb1
Name: scavenger receptor class B, member 1
Acc ID: CHEBI:16113
Term: cholesterol
Definition: A cholestanoid consisting of cholestane having a double bond at the 5,6-position as well as a 3beta-hydroxy group.
Chemical ID: MESH:D002784
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Scarb1affects transportEXP 6480464CTDSCARB1 protein affects the transport of CholesterolPMID:26651060
Scarb1multiple interactionsEXP 6480464CTD[Dietary Fats co-treated with Cholesterol] results in decreased expression of SCARB1 mRNA; Losartan inhibits the reaction [[Dietary Fats co-treated with Cholesterol] results in decreased expression of SCARB1 mRNA]PMID:18302760
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