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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61805
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fgf7
Name: fibroblast growth factor 7
Acc ID: CHEBI:16113
Term: cholesterol
Definition: A cholestanoid consisting of cholestane having a double bond at the 5,6-position as well as a 3beta-hydroxy group.
Chemical ID: MESH:D002784
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fgf7multiple interactionsEXP 6480464CTD[1,2-dioleoyloxy-3-(trimethylammonium)propane co-treated with Cholesterol] results in increased expression of FGF7 proteinPMID:16034455
Fgf7multiple interactionsISOFGF7 (Homo sapiens)6480464CTDCholesterol inhibits the reaction [FGF7 protein results in increased expression of FAS mRNA]; Cholesterol inhibits the reaction [FGF7 protein results in increased expression of SCD mRNA]PMID:16162944
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