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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1348698
Species: Homo sapiens
RGD Object: Gene
Symbol: NCF1
Name: neutrophil cytosolic factor 1
Acc ID: CHEBI:16113
Term: cholesterol
Definition: A cholestanoid consisting of cholestane having a double bond at the 5,6-position as well as a 3beta-hydroxy group.
Chemical ID: MESH:D002784
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NCF1increases expressionISONcf1 (Mus musculus)6480464CTDCholesterol results in increased expression of NCF1 mRNA; Cholesterol results in increased expression of NCF1 proteinPMID:19028402
NCF1multiple interactionsISONcf1 (Mus musculus)6480464CTDCholesterol inhibits the reaction [irbesartan results in increased expression of NCF1 mRNA]; Cholesterol inhibits the reaction [irbesartan results in increased expression of NCF1 protein]PMID:19028402
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