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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1349615
Species: Homo sapiens
RGD Object: Gene
Symbol: PECAM1
Name: platelet and endothelial cell adhesion molecule 1
Acc ID: CHEBI:16112
Term: chlorogenic acid
Definition: A cinnamate ester obtained by formal condensation of the carboxy group of trans-caffeic acid with the 3-hydroxy group of quinic acid. It is an intermediate metabolite in the biosynthesis of lignin.
Chemical ID: MESH:D002726
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PECAM1multiple interactionsISOPecam1 (Rattus norvegicus)6480464CTDChlorogenic Acid inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of PECAM1 protein]PMID:21414398
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