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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61992
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gch1
Name: GTP cyclohydrolase 1
Acc ID: CHEBI:16095
Term: sepiapterin
Definition: A pterin that has formula C9H11N5O3.
Chemical ID: MESH:C016727
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gch1multiple interactionsEXP 6480464CTDsepiapterin inhibits the reaction [[2, 4-diaminohypoxanthine results in decreased activity of GCH1 protein] which affects the susceptibility to Calcimycin]

PMID:12855421
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.