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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1308166
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp2c79
Name: cytochrome P450, family 2, subfamily c, polypeptide 79
Acc ID: CHEBI:160246
Term: aminophenazone
Definition: A pyrazolone that is 1,2-dihydro-3H-pyrazol-3-one substituted by a dimethylamino group at position 4, methyl groups at positions 1 and 5 and a phenyl group at position 2. It exhibits analgesic, anti-inflammatory, and antipyretic properties.
Chemical ID: MESH:D000632
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp2c79decreases methylationISORGD:16065896480464CTDCYP2C8 protein results in decreased methylation of Aminopyrine

PMID:26763401
Cyp2c79multiple interactionsISORGD:16065896480464CTDAmoxicillin inhibits the reaction [CYP2C8 protein results in decreased methylation of Aminopyrine] Piperacillin inhibits the reaction [CYP2C8 protein results in decreased methylation of Aminopyrine]

PMID:26763401
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