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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736208
Species: Homo sapiens
RGD Object: Gene
Symbol: CEBPB
Name: CCAAT enhancer binding protein beta
Acc ID: CHEBI:15940
Term: nicotinic acid
Definition: A pyridinemonocarboxylic acid that is pyridine in which the hydrogen at position 3 is replaced by a carboxy group.
Chemical ID: MESH:D009525
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CEBPBdecreases expressionISOCebpb (Mus musculus)6480464CTDNiacin results in decreased expression of CEBPB mRNA; Niacin results in decreased expression of CEBPB proteinPMID:21236357
CEBPBmultiple interactionsISOCebpb (Mus musculus)6480464CTD[Niacin inhibits the reaction [CEBPB protein binds to PTGS2 promoter]] which results in decreased expression of PTGS2 mRNA; Niacin inhibits the reaction [CEBPB protein binds to PTGS2 promoter]PMID:21236357
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