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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735341
Species: Homo sapiens
RGD Object: Gene
Symbol: CDKN1A
Name: cyclin dependent kinase inhibitor 1A
Acc ID: CHEBI:15940
Term: nicotinic acid
Definition: A pyridinemonocarboxylic acid that is pyridine in which the hydrogen at position 3 is replaced by a carboxy group.
Chemical ID: MESH:D009525
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CDKN1Aincreases expressionISOCdkn1a (Rattus norvegicus)6480464CTDNiacin deficiency results in increased expression of CDKN1A proteinPMID:17516866
CDKN1Amultiple interactionsISOCdkn1a (Rattus norvegicus)6480464CTDEtoposide promotes the reaction [Niacin deficiency results in increased expression of CDKN1A protein]PMID:17516866
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