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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1306305
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tjp1
Name: tight junction protein 1
Acc ID: CHEBI:15939
Term: glycyrrhizinic acid
Definition: A triterpenoid saponin that is the glucosiduronide derivative of 3beta-hydroxy-11-oxoolean-12-en-30-oic acid.
Chemical ID: MESH:D019695
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tjp1multiple interactionsISOTjp1 (Mus musculus)6480464CTDGlycyrrhizic Acid inhibits the reaction [Glucose results in decreased expression of TJP1 protein]; Glycyrrhizic Acid inhibits the reaction [Palmitic Acid results in decreased expression of TJP1 protein]PMID:27689324 PMID:27783111
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