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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 727892
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cdkn1c
Name: cyclin-dependent kinase inhibitor 1C
Acc ID: CHEBI:15930
Term: atrazine
Definition: A diamino-1,3,5-triazine that is 1,3,5-triazine-2,4-diamine substituted by a chloro group at position 6 while one of hydrogens of each amino group is replaced respectively by an ethyl and a propan-2-yl group.
Chemical ID: MESH:D001280
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cdkn1cdecreases expressionEXP 6480464CTDAtrazine results in decreased expression of CDKN1C mRNAPMID:26331294
Cdkn1cincreases expressionISOCDKN1C (Homo sapiens)6480464CTDAtrazine results in increased expression of CDKN1C mRNAPMID:22378314
Cdkn1cmultiple interactionsISOCDKN1C (Homo sapiens)6480464CTD[Atrazine co-treated with Arsenates] results in increased expression of CDKN1C mRNAPMID:18585445
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