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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3245
Species: Rattus norvegicus
RGD Object: Gene
Symbol: S100a4
Name: S100 calcium-binding protein A4
Acc ID: CHEBI:15930
Term: atrazine
Definition: A diamino-1,3,5-triazine that is 1,3,5-triazine-2,4-diamine substituted by a chloro group at position 6 while one of hydrogens of each amino group is replaced respectively by an ethyl and a propan-2-yl group.
Chemical ID: MESH:D001280
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
S100a4decreases expressionISOS100A4 (Homo sapiens)6480464CTDAtrazine results in decreased expression of S100A4 mRNAPMID:24211529
S100a4increases expressionISOS100A4 (Homo sapiens)6480464CTDAtrazine results in increased expression of S100A4 mRNAPMID:22378314
S100a4multiple interactionsISOS100A4 (Homo sapiens)6480464CTDAtrazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of S100A4 mRNA]PMID:24211529
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