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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1332312
Species: Mus musculus
RGD Object: Gene
Symbol: Xbp1
Name: X-box binding protein 1
Acc ID: CHEBI:15930
Term: atrazine
Definition: A diamino-1,3,5-triazine that is 1,3,5-triazine-2,4-diamine substituted by a chloro group at position 6 while one of hydrogens of each amino group is replaced respectively by an ethyl and a propan-2-yl group.
Chemical ID: MESH:D001280
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Xbp1affects splicingEXP 6480464CTDAtrazine affects the splicing of XBP1PMID:25259610
Xbp1multiple interactionsEXP 6480464CTDMelatonin inhibits the reaction [Atrazine affects the splicing of XBP1]PMID:25259610
Xbp1increases expressionISOXBP1 (Homo sapiens)6480464CTDAtrazine results in increased expression of XBP1 mRNAPMID:22378314
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